EEPRU Reports
Hernandez Alava, M., Pudney, S., Wailoo, A. (2023) Ethnicity, socio-economic status and health. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Report 069.
Harnan, S., Kearns, B., Scope, A., Schmitt, L., Jankovic, D., Hamiltonm J., Wong, R., Srivastava, T., Hill H, Chang Ku, C., Ren, K., Rothery, C., Bojke, L., Sculpher, M., Woods, B. (2022) Final report for the technology evaluation of ceftazidime with avibactam for treating severe aerobic Gram-negative bacterial infections. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 067
Woods, B., Schmitt, L., Jankovic, D., Kearns, B., Scope, A., Ren, K., Wong, R., Srivastava, T., Chang Ku, C., Hamiltonm J., Rothery, C., Bojke, L., Sculpher, M., Harnan, S. (2022) Final report for the technology evaluation of cefiderocol for treating severe aerobic Gram-negative bacterial infections. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 068 [CEFI Appendices ]
Hill H, Kearns B, Duffy S, Pashaya N, Sasieni P, Offman J (2022) Estimating the cost-effectiveness of risk stratified breast cancer screening in the UK. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Report 066.
Woods B, Lomas J, Sculpher M, Weatherly H, Claxton K, (2022) Achieving dynamic efficiency in pharmaceutical innovation: identifying the optimal share of value, the payments required and evaluating pricing policies. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Report 065
Hill H, Rowen D, Keetharuth D, and Wailoo A, (2022) A literature review of methods to Measure and value benefits in cost-effectiveness analyses of interventions for patients with either a short life expectancy or receiving palliative care. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Report 064
Hernández Alava, M., Pudney, S. and Wailoo, A. (2020) Estimating the relationship between EQ-5D-5L and EQ-5D-3L: results from an English population study (PDF, 1.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Report 063.
Faria, R., Martyn-St James, M., Wong, R., Scope, A., Sculpher, M., (2019) Evidence for the impact of interventions for, and medicines reconciliation in, problematic polypharmacy: a rapid review of systematic reviews and scoping searches (PDF, 2.5MB), Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 062.
Lomas, J., Martin, S., Claxton, K. (2018) Estimating the marginal productivity of the English National Health Service from 2003–04 to 2012–13 (PDF, 4.4MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Report 061.
Hernández-Alava, M., Pudney, S., Wailoo, A. (2018) Quality review of a proposed EQ-5D-5L value set for England, Policy Research Unit in Economic Evaluation of Health and Care Interventions (PDF, 2MB). Universities of Sheffield and York. EEPRU Research Report 060.
Rothery, C., Woods, B., Schmitt, L., Claxton, K., Palmer, S., Sculpher, M. (2018) Framework for value assessment of new antimicrobials. Implications of alternative funding arrangements for NICE Appraisal (PDF, 4MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 059.
Soares, M., Sculpher, M., Claxton, K. (2018) Health opportunity costs: assessing the implications of uncertainty using elicitation methods with experts (PDF, 3.2MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York.
Hinde, S., Griffin, S. (2018) ACE: Economic evaluation of the proactive lung cluster (PDF, 451KB), Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York.
Elliott, R., Camacho, E., Campbell, F., Jankovic, D., St James, M., Kaltenthaler, E., Wong, R., Sculpher, M., Faria, R. (2018) Prevalence and economic burden of medication errors in the NHS in England. Rapid evidence synthesis and economic analysis of the prevalence and burden of medication error in the UK (PDF, 2.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York.
Keetharuth, A., Galvan, C., Ara, R. (2017) Excess treatment costs (ETC) estimating the magnitude and distribution of ETC in England to inform policy formulation (PDF, 2.6MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York (September 2017).
Keetharuth, A., Brazier, J., Connell, J., Carlton, J., Taylor Buck, E., Ricketts, T,. Barkham, M. (2017) Development and validation of the Recovering Quality of Life (ReQoL) outcome measure (PDF, 2MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions, Universities of Sheffield and York. EEPRU Research Report 050, March 2017.
Walker, S., Gutacker, N., Sculpher, M. (2017) A scoping review on the production of different aspects of quality of health care (PDF, 537KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions, Universities of Sheffield and York. EEPRU Research Report 053, February 2017.
Faria, R. et al. (2016) Tool to calculate the cost-effective strategy for user-defined prices and cost-effectiveness thresholds (xlsm, 477KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions, Universities of Sheffield and York. EEPRU Research Report 047.
Mukuria, C., Peasgood, T., Rowen, D., Brazier, J. (2016) An empirical comparison of wellbeing measures used in the UK (PDF, 1.8MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions, Universities of Sheffield and York. EEPRU Research Report 048.
Spackman, E., Hinde, S., Bojke, L., Payne, K., Sculpher, M. (2015) Cost-effective analysis of genomic tests: what are the methods challenges? (PDF, 1.1MB), Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 028. Policy/paper document 02/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme (PDF, 1.2MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 029. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix C – Irritable bowel disease (PDF, 920KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 030. Policy/paper document 2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix D – Epilepsy (PDF, 1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 031. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix E – Diabetes (PDF, 1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 032. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix F – Bowel cancer (PDF, 932KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 033. Policy/paper document 2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix G – Head and neck cancer (PDF, 828KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 034. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix H – Psychological therapies (PDF, 992KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 035. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix I – Schizophrenia (PDF, 1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 036. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix J – Dementia (PDF, 879KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 037. Policy/paper document 01/03/2015.
Ara, R., Duarte, A., Harnan, S., Leaviss, J., Palmer, S., Sculpher, M., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work package 1. What patient reported outcome measures should be used in the 2013–14 National Clinical Audit Programme. Appendix K – Cardiovascular (PDF, 1.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 038. Policy/paper document 01/03/2015.
Keetharuth, A., Mulhern, B., Wong, R., Ara, R., Franklin, M., Jones, G., Brazier, J. (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audit Work package 2. How should PROMS data be collected? (PDF, 1.1MB), Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 039. Policy/paper document 01/03/2015.
Roberts, G. (2015) Estimating the “wider societal impacts” of health conditions and treatments (PDF, 1.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 040. Policy/paper document 1/10/2015.
Stevens, K., Brazier, J., Rowen, D. (2015) Estimating an exchange rate between the EQ-5D-3L and ASCOT (PDF, 824KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 41. Policy/paper document 01/10/2015.
Faria, R., Woods, B., Griffin, S., Palmer, S., Ryder, S., Sculpher, M. (2015) Economic analysis to support NHS implementation of hepatitis C drugs. Prioritisation of the treatment options for patients chronic hepatitis C at the METAVIR F3 stage (PDF, 2.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 045. Policy paper/document. 01/12/2015.
Faria, R., Barbieri, M., Griffin, S., Palmer, S., Sculpher, M. (2015) Economic analyses to support NHS implementation of hepatitis C drugs: scoping study (PDF, 1.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 046. Policy paper/document. 01/05/2015.
Ara, R., Brazier, J., Sculpher, M., Manca, A., Bjoke, L., Preston, L., Basarir, H. (2015) A framework for conducting economic evaluations when using patient decision aids in health care decision making (PDF, 1.2MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 049.
Rowen, D., Brazier, J., Mukuria, C., Keetharuth, A., Rise Hole, A., Tsuchiya, A., Whyte, S., Shackley, P. (2014) Update: Eliciting societal preferences for weighting QALY’s according to burden of illness, size of gain and end of life (PDF, 181KB), Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 018. Policy paper/document published 01/03/2014.
Barbieri, M., Richardson, G., Paisley, S., Sculpher, M. (2014) Rapid review of existing literature on the cost-effectiveness of alternative systems for diagnosis and referral of any cancer in primary care (PDF, 835KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 020. Policy paper/document published 01/09/2014.
Barbieri, M., Richardson, G., Paisley, S., Sculpher, M. (2014) Rapid review of existing literature on the cost-effectiveness of follow-up strategies after cancer treatment (PDF, 961KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 021. Policy paper/document published 01/09/2014.
Peasgood, T., Brazier, J., Mukuria, C., Rowen, D. (2014) A conceptual comparison of well-being measures used in the UK (PDF, 1.1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 026. Policy paper/document 01/09/2014.
Mukuria, C., Rowen, D., Peasgood, T., Brazier, J. (2014) Appendix 2 – Measures used in empirical comparison of well-being measures used in UK general population surveys (PDF, 891KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. Policy paper/document 027, published 01/10/2014.
Kearns, B., Rafia, R., Leaviss, J., Preston, L., Wong, R., Brazier, J. E., Palmer, S., Ara, R. (2014) Whole pathway modelling of depression in patients. Theme 2: Mental Health. Part 1: Executive summary, introduction, clinical reviews and conceptual modelling (PDF, 971KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 042. Policy/paper document 01/06/2014.
Kearns, B., Rafia, R., Leaviss, J., Preston, L., Wong, R., Brazier, J. E., Palmer, S., Ara, R. (2014) Whole pathway modelling of depression in patients. Theme 2: Mental Health. Part 2: Independent economic evaluation: methods and results, discussion and conclusion (PDF, 968KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 043. Policy paper/document 01/06/2014.
Kearns, B., Rafia, R., Leaviss, J., Preston, L., Wong, R., Brazier, J. E., Palmer, S., Ara, R. (2014) Whole pathway modelling of depression in patients. Theme 2: Mental Health. Appendices (PDF, 967KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 044. Policy paper/document 01/06/2014.
Faria, R., Walker, S., Whyte, S., Dixon, S., Palmer, S., Sculpher, M. (2014) Getting cost-effective technologies into practice: the value of implementation. An application to novel anticoagulants in the prevention of stroke and systemic embolism (PDF, 1.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 022. Policy paper/document published 01/09/2014.
Walker, S., Faria, R., Whyte, S., Dixon, S., Palmer, S., Sculpher, M. (2014) Getting cost-effective technologies into practice: the value of implementation. Report on framework for valuing implementation initiatives (PDF, 712KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 024. Policy paper/document 01/08/2014.
Whyte, S., Dixon, S., Faria, R., Walker, S., Palmer, S., Sculpher, M. (2014) Getting cost-effective technologies into practice: the value of implementation. An application to B-type natriuretic peptide (BNP) testing in diagnosing chronic heart failure (PDF, 1.1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 025. Policy paper/document 01/08/2014.
Sculpher, M., Walker, S., Hinde, S., Claxton, K. (2014) Research to inform resource allocation in health and social care (PDF, 1.1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 017. Policy paper/document published 01/01/2014.
Faria, R., Barbieri, M., Light, K., Sculpher, M. (2014). Economics of medicines optimisation (PDF, 1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 016. Policy paper/document published 01/01/2014.
Walker, S., Dixon, S., Palmer, S., Sculpher, M. (2013) Getting cost-effectiveness technologies into practice: the value of implementation (PDF, 548KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 014. Policy paper/document published 30/12/2013.
Essat, M., Faria, R., Gomersall, T., Grimm, S., Keetharuth, A., Walker, S., Dixon, S., Palmer, S., Sculpher, M. (2013) Getting cost effectiveness technologies into practice: the value of implementation. Initial scoping review for phase 1 (PDF, 1.5MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 005. Policy paper/document published 30/04/2013.
Ara, R., Barbieri, M., Weatherly, H., Essat, M., Basarir, H., Keethrauth, A., Cantrell, A., Sculpher, M., Brazier, J. (2013) A rapid review of the cost-effectiveness of interventions across the cancer patient pathways: radiotherapy and surgery (PDF, 1.4MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 006. Policy paper/document published 01/06/2013.
Mukuria, C., Rowen, D., Hernandez, M., Dixon, S. (2013) Examining productivity losses associated with health related quality of life using patient data (PDF, 1.4MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 013. Policy paper/document published 01/10/2013.
Ara, R., Kearns, B., Mukuria, C., van Hout, B., Brazier, J. (2013) Examining productivity losses associated with health related quality of life using patient and general population data (PDF, 1.1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 008. Policy paper/document published 01/10/2013.
Brazier, J., Rowen, D., Murkuria, C., Whyte, S., Keetharuth, A., Rise Hole, A., Tsuchiya, A., Shackley, P. (2013) Eliciting societal preferences for burden of illness, therapeutic improvement and end of life for value based pricing: a report of the main survey (PDF, 1.1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 011. Policy paper/document published 01/10/2013.
Rowen, D., Dixon, S., Hernandez, M., Mukuria, C. (2013) Estimating informal care effects associated with EQ-5D tariff values for use in economic evaluation (PDF, 787KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 012. Policy paper/document published 30/10/2013.
Tappenden, P., Bessey, A., McKenna, C., Sculpher, M. (2013) The likely impact of earlier diagnosis of cancer on costs and benefits to the NHS (PDF, 526KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 015. Policy paper/document published 01/11/2013.
Ara, R., van Hout, B., Kearns, B., Brazier, J. E. (2013) Case-mix methodology for the NHS outcomes framework GP patient survey questionnaire data (PDF, 1.3MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 007. Published March 2013.
Whyte, S., Harnan, S., Scope, A., Simpson, E., Tappenden, P., Duffy, S., Rachet, B., Sculpher, M., Hinde, S., McKenna, C., Wong, R. (2012) Early awareness interventions for cancer: colorectal cancer (PDF, 1.1MB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York and Cancer Awareness, Screening and Early Diagnosis (CASED) EEPRU Research Report 004. November 2012.
Hinde, S., McKenna, C., Whyte, S., Peake, M., Callister, M., Rogers, T., Sculpher, M. (2012) Modelling the cost-effectiveness of early awareness interventions for the early detection of lung cancer (PDF, 810KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 003. Policy paper/document published 01/11/2012.
Ara, R., Keetharuth, A. D., Papaioannou, D., Cantrell, A. J. and Brazier, J. (2011) Evaluating public health interventions for obesity from the perspective of local health authorities (PDF, 575KB). Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 001. Policy paper/document published 01/04/2011.
Epstein, D., Claxton, K., Sculpher, M. and Rice, N. (2011) Estimates of the relationship between health and income. Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York; EEPRU Research Report 002. Policy paper/document published 14/03/2011.