Validation of the EQ-5D-5L valuation set

Project theme: Outcomes measurement

Prior to making any recommendation to use the 5L, there is a requirement for public decision makers to take steps to quality assure the underlying models, appropriate to the level of risk and consistent with the Macpherson report.

EEPRU were asked to undertake quality assurance of the published value set for England. Below you will find the EEPRU report, independent referee comments, EEPRU responses to those comments and EEPRU responses to review from the EQ5D-5L valuation research team.

Project team

Monica Hernandez, Steve Pudney and Allan Wailoo.


Allan Wailoo


Hernández-Alava, M., Pudney, S. and Wailoo, A (2018) Quality review of a proposed EQ-5D-5L value set for England (PDF, 2MB), Policy Research Unit in Economic Evaluation of Health and Care Interventions. Universities of Sheffield and York. EEPRU Research Report 060. DOI:

Anonymous referee reports

Referee report 01 (PDF, 82KB)

Referee report 02 (PDF, 249KB)

Referee report 03 (PDF, 240KB)

Referee report 04 – redacted (PDF, 492KB)

Referee report 05 (PDF, 179KB)

Response from Devlin et al.

Response to: Quality review of a proposed EQ-5D-5L value set for England (PDF, 423KB)


EEPRU responses to referee reports – redacted (PDF, 439KB)

EEPRU responses to Devlin et al. (PDF, 475KB)

EQ5D-3LdData quality issues

EQ5D-3L data quality issues (PDF, 144KB)

Hernandez, M., Pudney, S. and Wailoo, A. (2020) The EQ-5D-5L value set for England: findings of a quality assurance program, Value in Health, Preferenced-Based Assessments, 23(5), pp. 642-648, 1 May 2020. doi: