Assessing the psychometric properties of EQ-5D-5L in people living with dementia
Assessing the psychometric properties of EQ-5D-5L in people living with dementia
Project theme: Outcomes
Having the right outcome measures to adequately capture the benefits of treatments in the area of dementia to ensure the efficient allocation of resources is of increasing importance given the increasing number of individuals with the condition. Concerns have been expressed in the literature around the suitability of existing preference-based measures (PBM) to compute quality adjusted life years in a population living with dementia.
The proposed work is to address this evidence gap. This review is the first project constituting the framing sample to identify studies for the subsequent two projects under this theme. (Project 2 - Explore psychometric solutions to put self-report and proxy reports for PBM on the same continuum in order to co-calibrate the two scores for use in a cost-effectiveness model. Project 3 - Assess the performance of EQ-5D-5L and EQ-5D-3L using available existing datasets across different severity groups and ages to make recommendations on the suitability of EQ-5D and to undertake head-to-head comparisons of at least two PBMs to add to the evidence base).
This project aims to conduct a systematic review to provide up to date evidence on the psychometric properties of EQ-5D-5L in people living with dementia.
Anju Keetharuth, Donna Rowen, Ruth Wong, Harry Hill
Keetharuth A, Hussain H, Rowen D, Wailoo A. (2022) “Assessing the psychometric performance of EQ-5D-5L in dementia: a systematic review", Health and Quality of Life Outcomes, 20, Article number: 139
Hussain H, Keetharuth AD, Rowen D, Wailoo A. (2022) Convergent validity of EQ-5D with core outcomes in dementia: a systematic review. Health Qual Life Outcomes 20, 152. https://doi.org/10.1186/s12955-022-02062-1